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Fig. 6 | Phytopathology Research

Fig. 6

From: Candidatus Phytoplasma ziziphi encodes non-classically secreted proteins that suppress hypersensitive cell death response in Nicotiana benthamiana

Fig. 6

The proposed model for the Candidatus Phytoplasma ziziphi bacterium deploying their ncSecPs to circumvent the host plant HR. As an intracellular bacterium, Ca. P. ziziphi secretes at least six ncSecPs that may target different plant subcellular compartments but work together to upregulate the gene expression of specific HR inhibitors, including pathogenesis-related proteins (PR-1, PR-2, and PR-5) and Bax inhibitor-1 (BI-1), via unknown mechanisms. The overexpressed HR inhibitors subsequently cause HR suppression, which favors colonization and infection of Ca. P. ziziphi. Blunt arrows indicate the negative impacts. ‘Cyt’ represents cytoplasm, while ‘N’ and ‘Nu’ indicate nucleus and nucleolus, respectively

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